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Polyubiquitin binding to ABIN1 is required to prevent autoimmunity
The protein ABIN1 possesses a polyubiquitin-binding domain homologous to that present in nuclear factor κB (NF-κB) essential modulator (NEMO), a component of the inhibitor of NF-κB (IκB) kinase (IKK) complex. To address the physiological significance of polyubiquitin binding, we generated knockin mi...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173241/ https://ncbi.nlm.nih.gov/pubmed/21606507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102177 |
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