Delta-like 1/Fetal Antigen-1 (Dlk1/FA1) Is a Novel Regulator of Chondrogenic Cell Differentiation via Inhibition of the Akt Kinase-dependent Pathway

Delta-like 1 (Dlk1, also known as fetal antigen-1, FA1) is a member of Notch/Delta family that inhibits adipocyte and osteoblast differentiation; however, its role in chondrogenesis is still not clear. Thus, we overexpressed Dlk1/FA1 in mouse embryonic ATDC5 cells and tested its effects on chondroge...

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Библиографические подробности
Главные авторы: Chen, Li, Qanie, Diyako, Jafari, Abbas, Taipaleenmaki, Hanna, Jensen, Charlotte H., Säämänen, Anna-Marja, Sanz, Maria Luisa Nueda, Laborda, Jorge, Abdallah, Basem M., Kassem, Moustapha
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173234/
https://ncbi.nlm.nih.gov/pubmed/21724852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230110
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