Small Angle Neutron Scattering Reveals pH-dependent Conformational Changes in Trichoderma reesei Cellobiohydrolase I: IMPLICATIONS FOR ENZYMATIC ACTIVITY

Cellobiohydrolase I (Cel7A) of the fungus Trichoderma reesei (now classified as an anamorph of Hypocrea jecorina) hydrolyzes crystalline cellulose to soluble sugars, making it of key interest for producing fermentable sugars from biomass for biofuel production. The activity of the enzyme is pH-depen...

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Main Authors: Pingali, Sai Venkatesh, O'Neill, Hugh M., McGaughey, Joseph, Urban, Volker S., Rempe, Caroline S., Petridis, Loukas, Smith, Jeremy C., Evans, Barbara R., Heller, William T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173226/
https://ncbi.nlm.nih.gov/pubmed/21784865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.263004
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