Small Angle Neutron Scattering Reveals pH-dependent Conformational Changes in Trichoderma reesei Cellobiohydrolase I: IMPLICATIONS FOR ENZYMATIC ACTIVITY

Cellobiohydrolase I (Cel7A) of the fungus Trichoderma reesei (now classified as an anamorph of Hypocrea jecorina) hydrolyzes crystalline cellulose to soluble sugars, making it of key interest for producing fermentable sugars from biomass for biofuel production. The activity of the enzyme is pH-depen...

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Autores principales: Pingali, Sai Venkatesh, O'Neill, Hugh M., McGaughey, Joseph, Urban, Volker S., Rempe, Caroline S., Petridis, Loukas, Smith, Jeremy C., Evans, Barbara R., Heller, William T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173226/
https://ncbi.nlm.nih.gov/pubmed/21784865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.263004
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