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Novel Function of Transcription Factor Nrf2 as an Inhibitor of RON Tyrosine Kinase Receptor-mediated Cancer Cell Invasion

Recepteur d' origine nantais (RON), a tyrosine kinase receptor, is aberrantly expressed in human tumors and promotes cancer cell invasion. RON receptor activation is also associated with resistance to tamoxifen treatment in breast cancer cells. Nrf2 is a positive regulator of cytoprotective gen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thangasamy, Amalraj, Rogge, Jessica, Krishnegowda, Naveen K., Freeman, James W., Ammanamanchi, Sudhakar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173176/
https://ncbi.nlm.nih.gov/pubmed/21799005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245746
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