COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding

Cullin RING ligases (CRLs), the most prolific class of ubiquitin ligase enzymes, are multimeric complexes that regulate a wide range of cellular processes. CRL activity is regulated by CAND1 (Cullin-associated Nedd8-dissociated protein 1), an inhibitor that promotes the dissociation of substrate rec...

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Autors principals: Mao, Xicheng, Gluck, Nathan, Chen, Baozhi, Starokadomskyy, Petro, Li, Haiying, Maine, Gabriel N., Burstein, Ezra
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173175/
https://ncbi.nlm.nih.gov/pubmed/21778237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278408
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