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Distinct Transcriptional Regulation of Human Large Conductance Voltage- and Calcium-activated K(+) Channel Gene (hSlo1) by Activated Estrogen Receptor α and c-Src Tyrosine Kinase
Estrogen receptor α (ERα) regulates gene transcription via “genomic” (binding directly or indirectly, typically via Sp1 or AP-1 sites, to target genes) and/or “nongenomic” (signaling) mechanisms. ERα activation by estrogen up-regulates the murine Ca(2+)-activated K(+) channel α subunit gene (mSlo1)...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173123/ https://ncbi.nlm.nih.gov/pubmed/21757754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.235457 |
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