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Specific Enzyme Complex of β-1,4-Galactosyltransferase-II and Glucuronyltransferase-P Facilitates Biosynthesis of N-linked Human Natural Killer-1 (HNK-1) Carbohydrate

Human natural killer-1 (HNK-1) carbohydrate is highly expressed in the nervous system and is involved in synaptic plasticity and dendritic spine maturation. This unique carbohydrate, consisting of a sulfated trisaccharide (HSO(3)-3GlcAβ1–3Galβ1–4GlcNAc-), is biosynthesized by the successive actions...

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Autors principals: Kouno, Tetsuya, Kizuka, Yasuhiko, Nakagawa, Naoki, Yoshihara, Toru, Asano, Masahide, Oka, Shogo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173110/
https://ncbi.nlm.nih.gov/pubmed/21771787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233353
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