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Fatty Acid Induced Remodeling within the Human Liver Fatty Acid-binding Protein
We crystallized human liver fatty acid-binding protein (LFABP) in apo, holo, and intermediate states of palmitic acid engagement. Structural snapshots of fatty acid recognition, entry, and docking within LFABP support a heads-in mechanism for ligand entry. Apo-LFABP undergoes structural remodeling,...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173104/ https://ncbi.nlm.nih.gov/pubmed/21757748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.270165 |
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