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N-Glycosylation Is Critical for the Stability and Intracellular Trafficking of Glucose Transporter GLUT4

The facilitative glucose transporter GLUT4 plays a key role in regulating whole body glucose homeostasis. GLUT4 dramatically changes its distribution upon insulin stimulation, and insulin-resistant diabetes is often linked with compromised translocation of GLUT4 under insulin stimulation. To elucida...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haga, Yoshimi, Ishii, Kumiko, Suzuki, Tadashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173088/
https://ncbi.nlm.nih.gov/pubmed/21757715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253955
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