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Human Tryptase Cleaves Pro-Nerve Growth Factor (Pro-NGF): HINTS OF LOCAL, MAST CELL-DEPENDENT REGULATION OF NGF/PRO-NGF ACTION

Several factors regulate nerve growth factor (NGF), which is formed from pro-NGF by intracellular and extracellular enzymatic cleavage. The close proximity between mast cells expressing the protease tryptase and NGF-producing smooth muscle-like peritubular cells in the testes of infertile patients l...

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Autors principals: Spinnler, Katrin, Fröhlich, Thomas, Arnold, Georg J., Kunz, Lars, Mayerhofer, Artur
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173076/
https://ncbi.nlm.nih.gov/pubmed/21768088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233486
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