Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis

Microsomal PGE synthase 1 (mPGES-1) is the terminal enzyme in the induced state of prostaglandin E(2) (PGE(2)) synthesis and constitutes a therapeutic target for rheumatoid arthritis (RA) treatment. We examined the role of the prostaglandin E synthase (PTGES) gene polymorphism in susceptibility to a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Korotkova, Marina, Daha, Nina A, Seddighzadeh, Maria, Ding, Bo, Catrina, Anca I, Lindblad, Staffan, Huizinga, Tom W J, Toes, Rene E M, Alfredsson, Lars, Klareskog, Lars, Jakobsson, Per-Johan, Padyukov, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172931/
https://ncbi.nlm.nih.gov/pubmed/21448233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.50
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados