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Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice

BACKGROUND: Viral replication as well as an immunopathological component are assumed to be involved in the development of coxsackie B virus (CBV)-induced myocarditis. We observed that mycophenolic acid (MPA), the active metabolite of the immunosuppressive agent mycophenolate mofetil (MMF), inhibits...

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Detalhes bibliográficos
Main Authors: Padalko, Elizaveta, Verbeken, Erik, Matthys, Patrick, Aerts, Joeri L, De Clercq, Erik, Neyts, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317291/
https://ncbi.nlm.nih.gov/pubmed/14687413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-3-25
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