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Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis

Most SOS mutagenesis in Escherichia coli is dependent on the UmuD and UmuC proteins. Perhaps as a consequence, the activity of these proteins is exquisitely regulated. The intracellular level of UmuD and UmuC is normally quite low but increases dramatically in lon(−) strains, suggesting that both pr...

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Bibliographic Details
Main Authors: Gonzalez, Martín, Frank, Ekaterina G., Levine, Arthur S., Woodgate, Roger
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC317269/
https://ncbi.nlm.nih.gov/pubmed/9869642
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