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Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I

Saccharomyces cerevisiae carries ∼150 copies of rDNA in tandem repeats. It was found that the absence of an essential subunit of RNA polymerase I (Pol I) in rpa135 deletion mutants triggers a gradual decrease in rDNA repeat number to about one-half the normal level. Reintroduction of the missing RPA...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Kobayashi, Takehiko, Heck, Denis J., Nomura, Masayasu, Horiuchi, Takashi
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.24.3821
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