c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

Ligand-induced down-regulation of two growth factor receptors, EGF receptor (ErbB-1) and ErbB-3, correlates with differential ability to recruit c-Cbl, whose invertebrate orthologs are negative regulators of ErbB. We report that ligand-induced degradation of internalized ErbB-1, but not ErbB-3, is m...

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Détails bibliographiques
Auteurs principaux: Levkowitz, Gil, Waterman, Hadassa, Zamir, Eli, Kam, Zvi, Oved, Shlomo, Langdon, Wallace Y., Beguinot, Laura, Geiger, Benjamin, Yarden, Yosef
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC317257/
https://ncbi.nlm.nih.gov/pubmed/9851973
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