The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAP(c) largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1
The RNA polymerases II and III snRNA gene promoters contain an octamer sequence as part of the enhancer and a proximal sequence element (PSE) as part of the core promoter. The octamer and the PSE bind the POU domain activator Oct-1 and the basal transcription factor SNAP(c), respectively. Oct-1, but...
Uloženo v:
| Vydáno v: | Genes Dev |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9832505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.22.3528 |
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