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A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation
We have identified a developmentally regulated, putative MEK kinase (MEKKα) that contains an F-box and WD40 repeats and plays a complex role in regulating cell-type differentiation and spatial patterning. Cells deficient in MEKKα develop precociously and exhibit abnormal cell-type patterning with an...
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| Publicado en: | Genes Dev |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9832508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.22.3564 |
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