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A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation

We have identified a developmentally regulated, putative MEK kinase (MEKKα) that contains an F-box and WD40 repeats and plays a complex role in regulating cell-type differentiation and spatial patterning. Cells deficient in MEKKα develop precociously and exhibit abnormal cell-type patterning with an...

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Bibliografiske detaljer
Main Authors: Chung, Chang Y., Reddy, T.B.K., Zhou, Kemin, Firtel, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC317245/
https://ncbi.nlm.nih.gov/pubmed/9832508
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