In Vivo Measurement of Normal Rat Intracellular Pyruvate and Lactate Levels after Injection of Hyperpolarized [1-(13)C]Alanine

Hyperpolarized technology utilizing dynamic nuclear polarization has enabled rapid and high sensitivity measurements of (13)C metabolism in vivo. The most commonly used in vivo agent for hyperpolarized (13)C metabolic imaging thus far has been [1-(13)C]pyruvate. In preclinical studies, not only is i...

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Autori principali: Hu, Simon, Zhu, Minhua, Yoshihara, Hikari A.I., Wilson, David M., Keshari, Kayvan R., Shin, Peter, Reed, Galen, von Morze, Cornelius, Bok, Robert, Larson, Peder E.Z., Kurhanewicz, John, Vigneron, Daniel B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172390/
https://ncbi.nlm.nih.gov/pubmed/21855243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mri.2011.07.001
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