The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7
TFIIH is a multisubunit complex, containing ATPase, helicases, and kinase activities. Functionally, TFIIH has been implicated in transcription by RNA polymerase II (RNAPII) and in nucleotide excision repair. A member of the cyclin-dependent kinase family, CDK7, is the kinase subunit of TFIIH. Geneti...
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| Publicado no: | Genes Dev |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317239/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9832506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.22.3541 |
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