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Self-assembly of E. coli MutL and its complexes with DNA

The E. coli MutL protein regulates the activity of several enzymes, including MutS, MutH and UvrD, during methyl-directed mismatch repair (MMR) of DNA. We have investigated the self association properties of MutL and its binding to DNA using analytical sedimentation velocity and equilibrium. Self as...

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Библиографические подробности
Главные авторы: Niedziela-Majka, Anita, Maluf, Nasib K., Antony, Edwin, Lohman, Timothy M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172365/
https://ncbi.nlm.nih.gov/pubmed/21793594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200753b
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