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Dissecting the Transcriptional Regulatory Properties of Human Chromosome 16 Highly Conserved Non-Coding Regions

Non-coding DNA conservation across species has been often used as a predictor for transcriptional enhancer activity. However, only a few systematic analyses of the function of these highly conserved non-coding regions (HCNRs) have been performed. Here we use zebrafish transgenic assays to perform a...

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Detalhes bibliográficos
Main Authors: Royo, José Luis, Hidalgo, Carmen, Roncero, Yolanda, Seda, María Angeles, Akalin, Altuna, Lenhard, Boris, Casares, Fernando, Gómez-Skarmeta, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172297/
https://ncbi.nlm.nih.gov/pubmed/21935474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024824
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