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H5N1 Influenza Virus Pathogenesis in Genetically Diverse Mice Is Mediated at the Level of Viral Load

The genotype of the host is one of several factors involved in the pathogenesis of an infectious disease and may be a key parameter in the epidemiology of highly pathogenic H5N1 influenza virus infection in humans. Gene polymorphisms may affect the viral replication rate or alter the host’s immune r...

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Detalhes bibliográficos
Main Authors: Boon, Adrianus C. M., Finkelstein, David, Zheng, Ming, Liao, Guochun, Allard, John, Klumpp, Klaus, Webster, Robert, Peltz, Gary, Webby, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171982/
https://ncbi.nlm.nih.gov/pubmed/21896679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00171-11
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