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Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

The promoter selectivity factor Sp1 often cooperates with other enhancer-binding proteins to activate transcription. To study the molecular underpinnings of these regulatory events, we have reconstituted in vitro the synergy observed in vivo between Sp1 and the sterol-regulated factor SREBP-1a at th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Näär, Anders M., Beaurang, Pierre A., Robinson, Karen M., Oliner, Jon D., Avizonis, Daina, Scheek, Sigrid, Zwicker, Jörk, Kadonaga, James T., Tjian, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317191/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765204/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.3020
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