Generation and characterization of a humanized PPARδ mouse model

BACKGROUND AND PURPOSE: Humanized mice for the nuclear receptor peroxisome proliferator-activated receptor δ (PPARδ), termed PPARδ knock-in (PPARδ KI) mice, were generated for the investigation of functional differences between mouse and human PPARδ and as tools for early drug efficacy assessment. E...

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Bibliografiske detaljer
Main Authors: Gross, B, Hennuyer, N, Bouchaert, E, Rommens, C, Grillot, D, Mezdour, H, Staels, B
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2011
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171871/
https://ncbi.nlm.nih.gov/pubmed/21426320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01359.x
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