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Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch

In mammals, the first branchial arch (BA1) develops into a number of craniofacial skeletal elements including the jaws and teeth. Outgrowth and patterning of BA1 during early embryogenesis is thought to be controlled by signals from its covering ectoderm. Here we used Cre/loxP technology to inactiva...

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Autors principals: Trumpp, Andreas, Depew, Michael J., Rubenstein, John L.R., Bishop, J. Michael, Martin, Gail R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317178/
https://ncbi.nlm.nih.gov/pubmed/10601039
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