Stroke With Transfusions Changing to Hydroxyurea (SWiTCH): A Phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overload

BACKGROUND: Stroke occurs in 5–10% of children with sickle cell anemia (SCA) and has a high (>50%) risk of recurrence without therapy. Chronic monthly erythrocyte transfusions effectively prevent recurrent stroke, but their long term use is limited by serious side effects, including iron overload...

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Detalhes bibliográficos
Main Authors: Ware, Russell E., Schultz, William H., Yovetich, Nancy, Mortier, Nicole A., Alvarez, Ofelia, Hilliard, Lee, Iyer, Rathi V., Miller, Scott T., Rogers, Zora R., Scott, J. Paul, Waclawiw, Myron, Helms, Ronald W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171640/
https://ncbi.nlm.nih.gov/pubmed/21826782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23145
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