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Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear
Atoh1 is required for differentiation of sensory hair cells in the vertebrate inner ear. Moreover, misexpression of Atoh1 is sufficient to establish ectopic sensory epithelia, making Atoh1 a good candidate for gene therapy to restore hearing. However, competence to form sensory epithelia appears to...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171634/ https://ncbi.nlm.nih.gov/pubmed/21801718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.07.019 |
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