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IL-1 acts on T cells to enhance the magnitude of in vivo immune responses

IL-1 strikingly enhances antigen-driven responses of CD4 and CD8 T cells. It is substantially more effective than LPS and when added to a priming regime of antigen plus LPS, it strikingly enhances cell expansion. The effect is mediated by direct action on CD4 and CD8 T cells; the response occurs whe...

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Detalhes bibliográficos
Main Authors: Ben-Sasson, S. Z., Caucheteux, Stephane, Crank, Michelle, Hu-Li, Jane, Paul, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171626/
https://ncbi.nlm.nih.gov/pubmed/21843950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.07.006
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