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The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans

Context-dependent gene silencing is used by many organisms to stably modulate gene activity for large chromosomal regions. We have used tandem array transgenes as a model substrate in a screen for Caenorhabditis elegans mutants that affect context-dependent gene silencing in somatic tissues. This sc...

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Detalhes bibliográficos
Main Authors: Hsieh, Jenny, Liu, Jing, Kostas, Stephen A., Chang, Chieh, Sternberg, Paul W., Fire, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317160/
https://ncbi.nlm.nih.gov/pubmed/10580003
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