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Genetic Risk for Malignant Hyperthermia in Non-Anesthesia-Induced Myopathies

Malignant hyperthermia (MH) is a pharmacogenetic, autosomal dominantly inherited disorder of skeletal muscle triggered by volatile anesthetics and infrequently by extreme exertion and heat exposure. MH has variable penetrance with an incidence ranging from 1 in 5,000 to 1 in 50,000–100,000 anesthesi...

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Detalhes bibliográficos
Main Authors: Vladutiu, Georgirene D., Isackson, Paul J., Kaufman, Kenneth, Harley, John B., Cobb, Beth, Christopher-Stine, Lisa, Wortmann, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171598/
https://ncbi.nlm.nih.gov/pubmed/21795085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.07.001
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