Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas

BACKGROUND: Most high-grade pelvic serous carcinomas (HGPSCs) arise from fallopian tube epithelium (FTE). To date, few markers have been shown to characterize FTE transformation. Stathmin 1 (STMN1) is a candidate oncogene whose activity is influenced by p53, p27Kip1 (p27), and PI3K/Akt pathway activ...

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Hlavní autoři: Karst, Alison M., Levanon, Keren, Duraisamy, Sekhar, Liu, Joyce F., Hirsch, Michelle S., Hecht, Jonathan L., Drapkin, Ronny
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171572/
https://ncbi.nlm.nih.gov/pubmed/21683992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.05.021
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