The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

The RING-H2 finger protein Rbx1 is a subunit of the related SCF (Skp1–Cdc53/Cul1–F-box protein) and von Hippel-Lindau (VHL) tumor suppressor (elongin BC–Cul2–VHL) E3 ubiquitin ligase complexes, where it functions as a component of Cdc53/Rbx1 and Cul2/Rbx1 modules that activate ubiquitination of targ...

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Detalles Bibliográficos
Main Authors: Kamura, Takumi, Conrad, Michael N., Yan, Qin, Conaway, Ronald C., Conaway, Joan Weliky
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Research Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC317157/
https://ncbi.nlm.nih.gov/pubmed/10579999
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