Cartilage Matrix Formation by Bovine Mesenchymal Stem Cells in Three-dimensional Culture Is Age-dependent

BACKGROUND: Cartilage degeneration is common in the aged, and aged chondrocytes are inferior to juvenile chondrocytes in producing cartilage-specific extracellular matrix. Mesenchymal stem cells (MSCs) are an alternative cell type that can differentiate toward the chondrocyte phenotype. Aging may in...

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Détails bibliographiques
Auteurs principaux: Erickson, Isaac E., van Veen, Steven C., Sengupta, Swarnali, Kestle, Sydney R., Mauck, Robert L.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2011
Sujets:
Symposium: Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171558/
https://ncbi.nlm.nih.gov/pubmed/21424832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-011-1869-z
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