Human Immunodeficiency Virus Envelope Protein Gp120 Induces Proliferation but Not Apoptosis in Osteoblasts at Physiologic Concentrations

Patients with HIV infection have decreased numbers of osteoblasts, decreased bone mineral density and increased risk of fracture compared to uninfected patients; however, the molecular mechanisms behind these associations remain unclear. We questioned whether Gp120, a component of the envelope prote...

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Detalhes bibliográficos
Main Authors: Cummins, Nathan W., Klicpera, Anna, Sainski, Amy M., Bren, Gary D., Khosla, Sundeep, Westendorf, Jennifer J., Badley, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171487/
https://ncbi.nlm.nih.gov/pubmed/21931863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024876
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