Resveratrol Suppresses Constitutive Activation of AKT via Generation of ROS and Induces Apoptosis in Diffuse Large B Cell Lymphoma Cell Lines

BACKGROUND: We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL). In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4′, 5-trihydroxystilbene), a nat...

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Detalles Bibliográficos
Main Authors: Hussain, Azhar R., Uddin, Shahab, Bu, Rong, Khan, Omar S., Ahmed, Saeeda O., Ahmed, Maqbool, Al-Kuraya, Khawla S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171480/
https://ncbi.nlm.nih.gov/pubmed/21931821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024703
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