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Drug therapy for hereditary cancers

Tumors arising in patients with hereditary cancer syndromes may have distinct drug sensitivity as compared to their sporadic counterparts. Breast and ovarian neoplasms from BRCA1 or BRCA2 mutation carriers are characterized by deficient homologous recombination (HR) of DNA, that makes them particula...

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Detalhes bibliográficos
Main Authors: Imyanitov, Evgeny N, Moiseyenko, Vladimir M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171323/
https://ncbi.nlm.nih.gov/pubmed/21819606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-9-5
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