Including Additional Controls from Public Databases Improves the Power of a Genome-Wide Association Study

Though genome-wide association studies (GWAS) have identified numerous susceptibility loci for common diseases, their use is limited due to the expense of genotyping large cohorts of individuals. One potential solution is to use ‘additional controls’, or genotype data from control individuals deposi...

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Detalhes bibliográficos
Main Authors: Mukherjee, Semanti, Simon, Jennifer, Bayuga, Sharon, Ludwig, Emmy, Yoo, Sarah, Orlow, Irene, Viale, Agnes, Offit, Kenneth, Kurtz, Robert C., Olson, Sara H., Klein, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171281/
https://ncbi.nlm.nih.gov/pubmed/21849791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330149
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