Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase and phospholipase Cγ signaling pathways

Signal transduction by the platelet-derived growth-factor receptor β (PDGFR-β) tyrosine kinase is required for proper formation of vascular smooth muscle cells (VSMC). However, the importance of individual PDGFR-β signal transduction pathways in vivo is not known. To investigate the role of two of t...

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Detalhes bibliográficos
Main Authors: Tallquist, Michelle D., Klinghoffer, Richard A., Heuchel, Rainer, Mueting-Nelsen, Peter F., Corrin, Philip D., Heldin, Carl-Henrik, Johnson, Richard J., Soriano, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317125/
https://ncbi.nlm.nih.gov/pubmed/11124809
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