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The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins

Neuropilin 1 (NRP1) is a transmembrane glycoprotein that is essential for blood vessel development in vertebrates. Best known for its ability to bind members of the vascular endothelial growth factor (VEGF) and class 3 semaphorin families through its extracellular domain, it also has a highly conser...

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Main Authors: Fantin, Alessandro, Schwarz, Quenten, Davidson, Kathryn, Normando, Eduardo M., Denti, Laura, Ruhrberg, Christiana
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171219/
https://ncbi.nlm.nih.gov/pubmed/21852397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070037
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