Consequences of PPAR(α) Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids

Glutathione (GSH) derives from cysteine and plays a key role in redox status. GSH synthesis is determined mainly by cysteine availability and γ-glutamate cysteine ligase (γGCL) activity. Because PPARα activation is known to control the metabolism of certain amino acids, GSH synthesis from cysteine a...

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Bibliographische Detailangaben
Hauptverfasser: Guelzim, Najoua, Huneau, Jean-François, Mathé, Véronique, Quignard-Boulangé, Annie, Martin, Pascal G., Tomé, Daniel, Hermier, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171156/
https://ncbi.nlm.nih.gov/pubmed/21915176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/256186
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