CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans

Microbial lipids activate T cells by binding directly to CD1 and T cell receptors (TCRs) or by indirect effects on antigen-presenting cells involving induction of lipid autoantigens, CD1 transcription, or cytokine release. To distinguish among direct and indirect mechanisms, we developed fluorescent...

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Bibliographische Detailangaben
Hauptverfasser: Kasmar, Anne G., van Rhijn, Ildiko, Cheng, Tan-Yun, Turner, Marie, Seshadri, Chetan, Schiefner, Andre, Kalathur, Ravi C., Annand, John W., de Jong, Annemieke, Shires, John, Leon, Luis, Brenner, Michael, Wilson, Ian A., Altman, John D., Moody, D. Branch
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2011
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171094/
https://ncbi.nlm.nih.gov/pubmed/21807869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110665
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