Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells

BACKGROUND: The KIAA1199 transcript is upregulated in colon adenomas and downregulated upon β-catenin knockdown. METHODS: Transcript profiling was performed on >500 colon biopsies, methylation profiling data were compared with transcript data. Immunohistochemistry assessed KIAA1199 protein expres...

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Main Authors: Birkenkamp-Demtroder, K, Maghnouj, A, Mansilla, F, Thorsen, K, Andersen, C L, Øster, B, Hahn, S, Ørntoft, T F
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170968/
https://ncbi.nlm.nih.gov/pubmed/21772334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.268
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