Targeting ErbB3-mediated stromal–epithelial interactions in pancreatic ductal adenocarcinoma

BACKGROUND: We sought to investigate the role of ErbB3-mediated signalling on the interaction between pancreatic cancer-associated fibroblasts (CAF) and carcinoma cells in an effort to disrupt tumourigenic pancreatic ductal adenocarcinoma (PDAC) stromal–epithelial cross-communication. METHODS: Prima...

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Detalhes bibliográficos
Main Authors: Liles, J S, Arnoletti, J P, Kossenkov, A V, Mikhaylina, A, Frost, A R, Kulesza, P, Heslin, M J, Frolov, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170963/
https://ncbi.nlm.nih.gov/pubmed/21792199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.263
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