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Reduced astrocytic contribution to the turnover of glutamate, glutamine, and GABA characterizes the latent phase in the kainate model of temporal lobe epilepsy

The occurrence of spontaneous seizures in mesial temporal lobe epilepsy (MTLE) is preceded by a latent phase that provides a time window for identifying and treating patients at risk. However, a reliable biomarker of epileptogenesis has not been established and the underlying processes remain unclea...

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Main Authors: Alvestad, Silje, Hammer, Janniche, Qu, Hong, Håberg, Asta, Ottersen, Ole Petter, Sonnewald, Ursula
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170943/
https://ncbi.nlm.nih.gov/pubmed/21522161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.36
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