LysoPC and PAF Trigger Arachidonic Acid Release by Divergent Signaling Mechanisms in Monocytes

Oxidized low-density lipoproteins (LDLs) play an important role during the development of atherosclerosis characterized by intimal inflammation and macrophage accumulation. A key component of LDL is lysophosphatidylcholine (lysoPC). LysoPC is a strong proinflammatory mediator, and its mechanism is u...

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Autori principali: Oestvang, Janne, Anthonsen, Marit W., Johansen, Berit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170782/
https://ncbi.nlm.nih.gov/pubmed/21912747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/532145
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