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Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Consequences of Adding an N-3 Methylcarbamoyl Group to the Diazepine Ring of 2,3-Benzodiazepine Derivatives
2,3-Benzodiazepine derivatives are AMPA receptor inhibitors, and they are potential drugs for treating some neurological diseases caused by excessive activity of AMPA receptors. Using a laser-pulse photolysis and rapid solution flow techniques, we characterized the mechanism of action of a 2,3-benzo...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170730/ https://ncbi.nlm.nih.gov/pubmed/21751782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2007977 |
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