Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma

BACKGROUND: Advanced stage head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with low survival rates. Loss-of-heterozygosity/allelic imbalance (LOH/AI) analysis has been widely used to identify genomic alterations in solid tumors and the tumor microenvironment (stroma). We hypoth...

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Bibliographic Details
Main Authors: Bebek, Gurkan, Orloff, Mohammed, Eng, Charis
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170587/
https://ncbi.nlm.nih.gov/pubmed/21884569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2043-9113-1-21
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