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Osteopontin Upregulation in Rotavirus-Induced Murine Biliary Atresia Requires Replicating Virus But is Not Necessary for Development of Biliary Atresia
Biliary atresia (BA) is a progressive fibro-inflammatory pediatric liver disease in which osteopontin (OPN), a glycoprotein with inflammatory and fibrogenic activity, may play a pathogenic role. The current studies were conducted in a mouse model of rotavirus-induced BA to test the hypotheses that l...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170515/ https://ncbi.nlm.nih.gov/pubmed/21742364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.05.015 |
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