Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

Oligodendrogliomas are the second most common malignant brain tumor in adults and exhibit characteristic losses of chromosomes 1p and 19q. To identify the molecular genetic basis for this alteration, we performed exomic sequencing of seven tumors. Among other changes, we found that the CIC gene (hom...

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Detalhes bibliográficos
Main Authors: Bettegowda, Chetan, Agrawal, Nishant, Jiao, Yuchen, Sausen, Mark, Wood, Laura D., Hruban, Ralph H., Rodriguez, Fausto J., Cahill, Daniel P., McLendon, Roger, Riggins, Gregory, Velculescu, Victor E., Oba-Shinjo, Sueli Mieko, Nagahashi Marie, Suely Kazue, Vogelstein, Bert, Bigner, Darell, Yan, Hai, Papadopoulos, Nickolas, Kinzler, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170506/
https://ncbi.nlm.nih.gov/pubmed/21817013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1210557
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