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The Role of Autophagy in Cancer: Therapeutic Implications

Autophagy is a homeostatic, catabolic degradation process whereby cellular proteins and organelles are engulfed into autophagosomes, digested in lysosomes and recycled to sustain cellular metabolism. Autophagy has dual roles in cancer, acting as both a tumor suppressor by preventing the accumulation...

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Detalhes bibliográficos
Main Authors: Yang, Zhineng J., Chee, Cheng E., Huang, Shengbing, Sinicrope, Frank A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170456/
https://ncbi.nlm.nih.gov/pubmed/21878654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0047
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